Investigating Linkage Disequilibrium in Collections of Plant
Cultivars and Accessions
Maria Joćo Paulo and
Fred van Eeuwijk
Institute for Plant Breeding Research, Cologne, Germany
Lab. of Plant Breeding, Wageningen University, Wageningen, The Netherlands
In recent years plant geneticists have
started to genotype historical collections of plant cultivars and accessions
for which they possessed already phenotypic information Subsequently,
diversity analyses and linkage disequilibrium analyses are performed on the
genotypic and phenotypic data. These analyses raise a number of problems
How to detect and quantify population
How to detect and quantify linkage disequilibrium between markers?
How to detect association between markers and traits?
How to account for multiple testing in linkage disequilibrium and
How to account for population substructure in
marker - trait association analyses?
In the presentation we will look at the analysis
of a data set and discuss problems and solutions related to the above